Table 1 Summary of ERβ protein expression in tissues.
From: Insufficient antibody validation challenges oestrogen receptor beta research
Cell types | Tissues | Level of positivity for a certain cell type |
|---|---|---|
Lymphocytes | Tonsil | Moderate to strong staining in few cells |
Lymph node | ||
Spleen | ||
Small intestine | ||
Appendix | ||
Colon | ||
Rectum | ||
Esophagus | ||
Granulosa cells | Ovary | Moderate staining in a subset of cells |
Decidua cells | Placenta | Weak to moderate staining in few cells |
Leydig cells | Testis | Weak to moderate staining in few cells |
Stromal cells | Selected normal tissues | Weak to moderate staining in few cells |
Endometrial cancer | Weak staining in subset of endothelial cells in 1/12 individuals | |
Tumour cells | Granulosa cell tumour | Weak to strong staining of most cells in 4/5 individuals |
Melanoma | Weak to moderate staining of few cells in 2/12 individuals | |
Thyroid cancer | Weak staining of few cells in 1/4 individuals |
