Table 1 Biological and physicochemical properties of materials used in this study.

From: Cooperative tumour cell membrane targeted phototherapy

Material

Lipid composition (molar ratio)

Hydrodynamic size* (nm)

Surface charge † (mV)

Blood half-life ‡ (h)

 

DMPC

PEG-PE

DOTAP

Biotin-PE/Alexa488-PE

   

FL

71.2

3.8

20

5

126.5

15.4

2.2

CL

75

0

20

5

135.0

45.9

–

PL

91.2

3.8

0

5

121.1

-10.3

16.1

SA

–

–

–

–

6.5

-4.2

14.3

  1. *Mean hydrodynamic sizes of the materials based on dynamic light scattering measurements (n=3).
  2. †Mean surface charges of the materials based on zeta-potential measurements (n=3).
  3. ‡Blood half-lives of the materials obtained by fitting blood fluorescence to a single-exponential equation for a one-compartment open pharmacokinetic model (n=3).
Back to article page