Table 1 Cancer genes not previously implicated in osteosarcoma.
Gene | Number of mutated samples ( n =112) | Truncating point mutation | Disruptive break point | Homozygous deletion | Amplicon |
|---|---|---|---|---|---|
DNM2 | 4 | 0 | 4 | 0 | 0 |
ERBB4 | 4 | 1 | 0 | 3 | 0 |
TERT | 4 | 0 | 0 | 0 | 4 |
ARID1B | 3 | 0 | 3 | 0 | 0 |
CCND2 | 3 | 0 | 0 | 0 | 3 |
IGF1R | 3 | 0 | 0 | 0 | 3 |
RBL2 | 3 | 2 | 1 | 0 | 0 |
SUFU | 3 | 1 | 2 | 0 | 0 |
FAS | 2 | 1 | 0 | 1 | 0 |
IGF2R | 2 | 2 | 0 | 0 | 0 |
MLL3 | 2 | 0 | 2 | 0 | 0 |
SETD2 | 2 | 1 | 1 | 0 | 0 |
