Figure 7: A hypothesis for explaining how vitamin E promotes muscle homeostasis. | Nature Communications

Figure 7: A hypothesis for explaining how vitamin E promotes muscle homeostasis.

From: Promotion of plasma membrane repair by vitamin E

Figure 7

Muscle contractions, especially high-force eccentric contractions, disrupt the plasma membranes (grey ovals) of myocytes and generate ROS. If sufficient vitamin E is present in the membranes of these injured myocytes, repair succeeds via a patch mechanism (red circles in myocytes) and they survive this injury. If, on the other hand, the myocyte is deficient in vitamin E, repair fails, injured myocytes die and eventually myopathy develops.

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