Table 1 Clonotypic composition of CD4+ T cells expanded using different Flu antigens.

From: Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection

TRBV

CDR3

TRBJ

Freq. (%)

Clonotypes of CD4+ T cells expanded using Flu1

6–51

CASSYSGGVGETQY

2–5

25.49

25–1

CASSDGTFTEAF

1–1

21.57

92

CASSMSPGPRESPLH

1–6

13.73

25–13

CASSDAGLGDYEQY

2–7

11.76

284

CASSPPGAGEGETQY

2–5

7.84

28

CASSLIAEEEGYGYT

1–2

3.92

28

CASSTTGSTDTQY

2–3

3.92

5–4

CASSLGLAGGGDTQY

2–3

1.96

28

CASTPGTGDVQPQH

1–5

1.96

5–65

CASSPLSQGVRGYT

1–2

1.96

28

CASSRTGSTDTQY

2–3

1.96

4–1

CASSTDRGPYEQY

2–7

1.96

24–1

CATSDESYGYT

1–2

1.96

Clonotypes of CD4+ T cells expanded using Flu2

25–13

CASSDAGLGDYEQY

2–7

32.43

28

CASSRLRGPYEQY

2–7

27.03

6–5

CASSYDPSPTYEQY

2–7

16.22

6–51

CASSYSGGVGETQY

2–5

13.51

284

CASSPPGAGEGETQY

2–5

2.70

92

CASSMSPGPRESPLH

1–6

2.70

25–1

CASSDAGLGDYEQY

2–3

2.70

30

CAYTTSGAVTDTQY

2–3

2.70

Clonotypes of CD4+ T cells expanded using Flu3

5–65

CASSPLSQGVRGYT

1–2

69.70

12–3/4

CASSEGFGAFQPQH

1–5

30.30

  1. Superscript numbers indicate identical clonotypes.
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