Figure 1: Hes5∷CreERT2 expression overlaps with Hes5∷GFP in DG NSCs. | Nature Communications

Figure 1: Hes5∷CreERT2 expression overlaps with Hes5∷GFP in DG NSCs.

From: Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1high intermediate progenitors

Figure 1

(a) In adult Hes5∷CreERT2 Hes5∷GFP double-transgenic mice, Hes5∷GFP+ cells in the SGZ express Cre-recombinase. (b) Quantification of Hes5∷GFP+ and Cre co-expression. (c) Both radial (arrows) and horizontal (arrowhead) Hes5∷GFP+ NSCs express Hes5∷CreERT2. (d) Cre activity is induced to lineage trace both radial and horizontal Hes5∷GFP+ NSCs, using the Rosa26R reporter allele (β-Gal). β-Gal, β-Galactosidase; GCL, granule cell layer; ML, molecular layer; SGZ, subgranular zone. Error bars are s.d. Scale bars in (a) equals 100 μm, in (c) and (d) equals20 μm.

Back to article page