Figure 2: Advillin-Cre does not affect inflammatory or neuropathic pain behaviour.
From: Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons
Advillin-Cre+/− (orange boxes/columns), littermates (white boxes/columns). (a,b) Behavioural responses of Advillin-Cre+/− (N=12) wild-type littermate (N=8) mice following intraplantar injection of 20 μl of 5% formalin. (c) von Frey 50% threshold response of Advillin-Cre+/− (N=9) and wild-type littermate (N=8) mice following intraplantar injection of 20 μl of complete Freund's adjuvant. (d) Hargreaves' test responses of Advillin-Cre+/− mice (N=9) and wild-type littermate (N=8) mice following intraplantar injection of 20 μl of complete Freund's adjuvant. (e) Hargreaves' test response of Advillin-Cre+/− mice (N=12) and wild-type littermates (N=10) mice following intraplantar injection of 20 μl of carrageenan. (f) von Frey 50% threshold response of Advillin-Cre+/− mice (N=12) and wild-type littermates (N=10) mice following L5 SNT. All data analysed by two-way analysis of variance followed by the Bonferroni post hoc test. Results are presented as mean±s.e.m.
