Figure 1: Phylogenetic distribution and the activity of PARG enzymes.
From: Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase
(a) The domain structure of canonical and bacterial type PARGs. (b) Poly(ADP-ribose) hydrolytic activities of Tetrahymena thermophila and human PARGs. The activity is dependent on the integrity of catalytic glutamate residues.
