Figure 5: EMT marker expression and epigenetic status of the ESRP1 locus in CD44v+ or CD44v− 4T1 cells. | Nature Communications

Figure 5: EMT marker expression and epigenetic status of the ESRP1 locus in CD44v+ or CD44v− 4T1 cells.

From: Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

Figure 5

(a) Immunoblot analysis of the epithelial markers (E-cadherin and ZO-1) and the mesenchymal markers (N-cadherin and Vimentin) and Twist expression in CD44v+ or CD44v− 4T1 cells. α-Tubulin was analysed as a loading control. (b) Enrichment of histone H3K4me3 and H3K27me3 as well as of RNA polymerase II (RNAP) at the ESRP1 locus on mouse chromosome 4 in CD44+ or CD44− 4T1 cells as visualized with the 390-kbp UCSC mm9 genome browser. The gene is transcribed from right to left.

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