Figure 2: miR-17-5p regulates proliferation and motility in LoVo cells. | Nature Communications

Figure 2: miR-17-5p regulates proliferation and motility in LoVo cells.

From: Elevated oncofoetal miR-17-5p expression regulates colorectal cancer progression by repressing its target gene P130

Figure 2

(a) qRT–PCR assay for miR-17-5p expression different treatment groups. (b) MTT assay for CRC cell proliferative activity in different treatment groups and different times after transfection. (c) Clonogenic assay for CRC cells proliferative activity in different treatment groups after transfection. Apoptosis (d) and TUNEL (e) assays showed that miR-17-5p suppressed cell apoptosis and G1 arrest. (f) Transwell assays found that miR-17-5p showed both of migration and invasion for LoVo cells in different treatment groups. These results are representative of at least three independent experiments. All bars represent the mean values±s.d. of three experiments.

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