Figure 4: Analysis of the BM and spleen cell lineages in the Sca1-HGAL mice. | Nature Communications

Figure 4: Analysis of the BM and spleen cell lineages in the Sca1-HGAL mice.

From: Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation

Figure 4

Cells from the BM and spleen of young (8 weeks) and old (more than 7-month-old) age-matched Sca1-HGAL mice and wild-type controls (n=11 in each group) were analysed by flow cytometry. (a) Total cell number of the indicated cell sub-populations in the BM and spleens of the young and old Sca1-HGAL and control mice. Data are presented as mean±s.d. of the mean. (b) Representative FACS plots of 12-month-old Sca1-HGAL mice are displayed. FACS definition of B-cell developmental stages was performed according to Kwon et al.37

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