Figure 6: Myc sites present in mitotic chromosomes associate with insulator proteins.
(a) Heatmaps showing chromatin features at Class I and Class II Myc sites. Each panel represents 2 kb upstream or downstream of the Myc sites. Signals are represented by the number of raw reads from ChIP-seq or enrichment log2 value from ChIP-chip for the listed proteins or histone modifications. (b) Heatmaps showing the overlap of the listed protein at the two classes of Myc sites. (c) Insulator proteins and Myc persist on chromatin during mitosis at Class II Myc sites. (d) Distribution of Class I and Class II Myc sites with respect to topological domain boundaries. The significance was examined for each distance category by the χ2-test (**P<0.01, *P<0.05).
