Figure 1: Aldara induces type I IFN- and TLR7-independent keratinocyte acanthosis and hyperproliferation. | Nature Communications

Figure 1: Aldara induces type I IFN- and TLR7-independent keratinocyte acanthosis and hyperproliferation.

From: Aldara activates TLR7-independent immune defence

Figure 1

(a,c) Quantification of acanthosis in the epidermis of WT129, A129, C57BL/6 and TLR7-ko mice. Error bars indicate s.d.; *P<0.05, **P<0.01 and ***P<0.001 (unpaired Student’s t-test), n=5, 2 separate experiments. (b,d) Hematoxylin and eosin (H&E) and Ki67 staining of skin of untreated or Aldara-treated WT129, A129, C57BL/6 and TLR7-ko mice. Scale bar, 50 μm.

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