Table 1 Survivor colonies and growth on GdnHCl abolish the effect of polyQ proteins on septins.

From: A network of genes connects polyglutamine toxicity to ploidy control in yeast

Morphology

pQ0 normal colonies (% of cells)

pQ56 normal colonies (% of cells)

pQ56 large colony 1 (% of cells)

pQ56 large colony 2 (% of cells)

pQ56 large colony 3 (% of cells)

pQ56 GdnHCl-treated colonies (% of cells)

No structure

22

17

20

25

24

45

Single ring

66

36

68

68

62

43

Granular

7

12

8

1

5

7

Single focus

4

12

3

4

7

4

≥2 Foci

1

23

1

2

2

1

  1. The table summarizes the data (% of cells in each category) visualized in Fig. 5c and additional readouts for three weakly fluorescent survivor colonies, as well as GdnHCl-treated cells. The data indicate that pica escape and GdnHCl therapy equally abolish the pica phenotype also on a molecular level.
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