Figure 1: Starvation-refeeding induced transient colonic EC hyperproliferation.
From: Microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice
(a) Colonic tissues were taken from mice fed ad libitum (control), mice starved for 36 h and mice starved for 36 h and refed with normal bait (CE2) for 2 or 24 h. Frozen sections were stained with hematoxylin and eosin (H&E; upper) and anti-BrdU antibody (lower, green). Scale bar, 200 μm. (b) Number of BrdU+ cells per five crypts was counted at each time point. Each dot indicates an individual mouse. Mann–Whitney test was performed for P-value.
