Figure 4: AFM images of plasmid DNA.
From: Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA delivery
AFM images in tapping mode on air showing the effects induced on pEGFP-C1 plasmid DNA folding by incubation with (a) 2 μM argininocalixarene 3a; (b) 1 μM argininocalixarene 6; (c) 2 μM lysinocalixarene 3b in presence of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine) 4 μM; and (d) image of pEGFP-C1 plasmid DNA 0.5 nM alone. Each image represents a 2 × 2 μm scan.
