Figure 3: Modulation of susceptibility to antibiotics by VOCs.
From: Interspecific bacterial sensing through airborne signals modulates locomotion and drug resistance
(a) Representative kinetic analysis of antibiotic susceptibility of E. coli cells from n=3 with P=0.05. PM pattern (left) and PM kinetics (right) of a PM12 plate. (b) Quantitative analysis of PM kinetics from PM11 to PM20. (c) Effect of VOCs on antibiotic resistance in E. coli. The relative survival ratio of VOC-treated to non-treated E. coli in ampicillin or tetracycline is shown. (d) Expression of hipA and hipB in the presence and absence of VOCs. Gene expression was monitored by RT-qPCR. Error bars are defined as s.e.m. from triplicate experiments. (e) Growth on ampicillin is dependent on hipA expression. VOCs did not improve survival in the hipA-knockout strain, whereas VOCs improved survival in the complemented strain. The plasmids pCA24N and ASKA-hipA were used50.
