Figure 1: Calfacilitin expression and regulation.
From: Calfacilitin is a calcium channel modulator essential for initiation of neural plate development
(a–f) Expression in the chick embryo at stages XII-10. Expression gradually becomes restricted to the central nervous system. (g, Top) A graft of Hensen’s node induces Calfacilitin; in section (g, bottom), Calfacilitin induction is seen in the host epiblast. (h, Top) FGF8 induces Calfacilitin; this is seen more clearly in section (h, bottom), which also reveals expression localized to the host epiblast next to the FGF8 bead. Scale bar, 300 μm in a; Scale bar, 100 μm in b,c,g,h; Scale bar, 120 μm in d,e; Scale bar, 500 μm in f, Scale bar, 60 μm in g bottom, h bottom.
