Figure 6: Effects of central ghrelin treatment in Gpr83 ko mice. | Nature Communications

Figure 6: Effects of central ghrelin treatment in Gpr83 ko mice.

From: The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

Figure 6

Body weight (a,b), cumulative food intake (c,d) and change of fat mass (e) of Gpr83 ko and wt mice treated chronically for 7 days via icv ghrelin infusion (5 nmol per day) in the lateral ventricle (N=6–7 mice per group). *P<0.05; **P<0.01; ***P<0.001 based on 2-way ANOVA followed by Bonferroni post-hoc test (a–d) or unpaired 2-tailed Student’s t-test (e). 2-way ANOVA p-value for overall treatment is P=0.027 (a), P=0.0047 (b), P=0.241 (c) and P=0.0082 (d). Data represent mean±s.e.m.

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