Table 2 Affinity of 2 for various biomolecules.

From: Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules

Biomolecule

K d (nM); stoichiometry

Biomolecule

K d (nM); stoichiometry

MBNL1

>>2,000

r(CAG)12

1400±0.2; 1.2±0.1

BSA

>>2,000

1 × 1 UU

530±0.1; 1.0±0.1

r(CUG)12

125±0.052; 6±0.4

AU

>>25,000