Table 2 Affinity of 2 for various biomolecules.
From: Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules
Biomolecule | K d (nM); stoichiometry | Biomolecule | K d (nM); stoichiometry |
---|---|---|---|
MBNL1 | >>2,000 | r(CAG)12 | 1400±0.2; 1.2±0.1 |
BSA | >>2,000 | 1 × 1 UU | 530±0.1; 1.0±0.1 |
r(CUG)12 | 125±0.052; 6±0.4 | AU | >>25,000 |