Figure 4: Changing the excitability of motoneurons reverses the gradient of dendritic dynamics but does not affect stable dendritic size.
From: Homeostatic regulation of dendritic dynamics in a motor map in vivo
(a) Plot of cell body position versus total number of filopodia extended in the 30-min imaging period for: 16 motoneurons expressing Kir2.1-viral2a-mGFP (red circles); 34 mGFP expressing motoneurons (grey circles); and 7 mutantKir2.1-viral2a-mGFP expressing motoneurons (blue circles). (b) Plot of position versus the sum of all filopodial extensions over the entire imaging period. (c) Plot of position versus filopodial dynamics normalized to the stable dendritic arbour length of the cell. (d) Plot of cell body position versus stable dendritic arbour length for each group. (e–g) Plots of retractions similar to those for extensions in a–c. (h) Schematic showing the inverted gradient of motoneuron dendritic dynamics as a consequence of decreasing the excitability of motoneurons.
