Figure 1: The carotid bodies in hypertensive rats are tonically active.
From: The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension
Comparing the effect of 100% oxygen to depress tonic CB activity in Wistar (n=6) and SH (n=6) rats on SBP (a) and RSA (b,c). The CB in SH rats, but not Wistar rats, exhibits tonic activity that is functionally relevant and contributes to basal arterial pressure (d) and sympathetic activity (e). Data are shown as mean±s.e.m. *P<0.05, repeated-measures analysis of variance.
