Figure 5: Unilateral carotid sinus denervation does not lower blood pressure in the rat.
From: The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension
Unilateral carotid sinus nerve denervation (CSD) was ineffective at lowering SBP in SH rats whether the left or right CB was removed (n=8; a). Irrespective of whether the left or right CB was removed first, there was no difference in the fall in SBP observed on removal of the contralateral CB (b). Note that time-staggered unilateral CB denervation does not affect the magnitude of the fall in SBP, which is the same as that seen when both left and right CB are denervated simultaneously (see Figs 2, 3). Data are shown as mean±s.e.m. **P<0.01, within-group analysis of variance.
