Figure 6: Carotid sinus and RD interaction time course.
From: The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension
Time profile of the SBP response to (a) renal nerve denervation (RD) followed by carotid sinus nerve denervation (CSD; n=6) and (b) CSD followed by RD resection in SH rats (n=7). Note the time-dependent increase in SBP in shams (n=6 and 7, respectively). The completeness of the CSD is shown by the absence of a reflex pressor and bradycardic response following i.v. injections of sodium cyanide (NaCN; c). Data are shown as mean±s.e.m., repeated-measures analysis of variance (ANOVA): *P<0.05, **P<0.01; between-group ANOVA, ##P<0.01.
