Figure 4: ARKO mice do not develop glucose-induced fatty liver. | Nature Communications

Figure 4: ARKO mice do not develop glucose-induced fatty liver.

From: Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

Figure 4

WT mice and AR KO given ad libitum normal chow diet with 10% glucose water, or tap water for 14 weeks (n=3–4). (a) Cumulative total energy intake of chow diet with 10% glucose water or tap water for 14 weeks. (b) Growth curves of WT mice and AR KO mice. (c) Liver weight. (d) Hepatic sorbitol content. (e) Hepatic fructose content. (f) Intrahepatic triglyceride levels. (g) Serum aspartate aminotransferase (AST) levels. (h) Serum alanine aminotransferase (ALT) levels. Data represent means±s.e.m. *P<0.05, **P<0.01, ***P<0.001 versus respective water control. #P<0.05. ##P<0.01. ###P<0.001 (analysis of variance, Tukey’s post hoc test).

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