Figure 3: Examples of new MXE candidates. | Nature Communications

Figure 3: Examples of new MXE candidates.

From: Expansion of the mutually exclusive spliced exome in Drosophila

Figure 3

(a) Exon–intron gene structures of example genes containing newly predicted internal MXEs. The isoforms of the vibrator gene are annotated in r5.48 and are supported by cDNA and RNA-Seq, the shaker gene splice variants are not annotated but supported by RNA-Seq, and the MXE candidate of the nicotinic Acetylcholine Receptor α 80B is not experimentally supported yet. (b) Exon–intron gene structure of the CG14608 gene containing two newly predicted internal MXEs that are supported by evidence through competing RNA secondary structures. All transcripts are represented 5′ to 3′. The colour coding is explained in the legend and applies to all gene structure figures. Coloured big bars represent mutually exclusive exons. The darkest coloured bar is the exon that was included in the query sequence, whereas the lighter coloured bars represent identified MXEs. The higher the similarity between the candidate and the query exon, the darker the colour of the candidate (100% identity would result in the same colour). The opacity of the colours of each alternative exon corresponds to the alignment score of the alternative exon to the original one.

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