Figure 5: Gonadal histology of GnRH-Cre;Gpr54f/f and littermate control Gpr54f/f mice.
From: Dependence of fertility on kisspeptin–Gpr54 signaling at the GnRH neuron
(a,b) Testis morphology in adult Gpr54f/f (a) and GnRH-Cre+/−; Gpr54f/f (b) mice. No spermatozoa are observed in the seminiferous tubules of the GnRH-Cre+/−; Gpr54f/f mice (b) as compared with the Gpr54f/f littermates; scale bars in a,b represent 100 μm (n=4–6 per group). (c,d) Ovarian morphology in adult Gpr54f/f (c) and GnRH-Cre+/−; Gpr54f/f (d) mice. Whereas corpora lutea were readily observed in the ovaries of Gpr54f/f mice (c), none were observed in the ovaries of GnRH-Cre+/−; Gpr54f/f mice (d); scale bars in c,d represent 1 mm (n=5 per group).
