Figure 6: Generation of Gpr54−/−-Tg rescue mice and selective targeting of transgene to GnRH neurons. | Nature Communications

Figure 6: Generation of Gpr54−/−-Tg rescue mice and selective targeting of transgene to GnRH neurons.

From: Dependence of fertility on kisspeptin–Gpr54 signaling at the GnRH neuron

Figure 6

(a) Schematic of the GnRH-BAC transgene harboring either GPR54 or GFP. (b) Dual immunofluorescence showing the expression of GFP (green) and GnRH (red) in the rostral preoptic area of a GnRH-BAC-GFP mouse. Note the complete overlap between GnRH cell body immunofluorescence and GFP expression. Scale bar =100 μm.

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