Figure 5: Invasive capacity of SCC-2 cells with loss- or gain-of-function of CTNNA2 and CTNNA3.

Left, representative microscopic (× 10 magnification) pictures of invasive cells after silencing (i), overexpression of wild-type (o) or overexpression of mutant forms of CTNNA2 and CTNNA3. Right, number of invasive cells for each cell line. Statistical analyses were performed by Student’s t-test with *P<0.05, **P<0.01 and ***P<0.005. Error bars represent mean±s.e.m. of three to five biological replicates. Scale bars, 50 μm.