Table 2 Somatic mutations affecting CTNNA2 and CTNNA3 in the validation series.
Gene | Case | Location | Mutation | Condel score | Condel prediction |
|---|---|---|---|---|---|
CTNNA2 | HN05 | Glottic | E76* | — | Truncating |
CTNNA2 | HN35 | Supraglottic | S132Y | 0.942 | Deleterious |
CTNNA2 | HN22 | Supraglottic | E266* | — | Truncating |
CTNNA2 | HN03 | Supraglottic | L434* | — | Truncating |
CTNNA2 | HN24 | Glottic | S597G | 0.792 | Deleterious |
CTNNA2 | L000 | Supraglottic | M725I | 0.645 | Deleterious |
CTNNA2 | L004 | Supraglottic | A761S | 0.367 | Neutral |
CTNNA3 | HN03 | Supraglottic | E413V | 0.652 | Deleterious |
CTNNA3 | HN67 | Supraglottic | A468P | 0.76 | Deleterious |
CTNNA3 | HN51 | Supraglottic | V492F | 0.591 | Deleterious |
CTNNA3 | HN56 | Supraglottic | V607L | 0.585 | Deleterious |
CTNNA3 | HN22 | Supraglottic | C622F | 0.689 | Deleterious |
CTNNA3 | L000 | Supraglottic | R628P | 0.645 | Deleterious |
CTNNA3 | HN56 | Supraglottic | D696N | 0.622 | Deleterious |
