Figure 9: Model of AtPAM16 as a subunit of mitochondria inner membrane import motor for negative regulation of plant immunity.
From: Mitochondrial AtPAM16 is required for plant survival and the negative regulation of plant immunity
(a) AtPAM16 normally facilitates import of an unknown negative regulator (?) into mitochondria during an immune response. This inhibition helps to prevent autoimmunity due to uncontrolled immune response, such as over-production of ROS. (b) With a mutation in AtPAM16, this negative regulator cannot be fully imported into mitochondria, thus leading to autoimmunity and ROS accumulation due to insufficient repression. Partial import of this negative regulator can still be achieved through AtPAM16L.
