Figure 6: ^37,43Gap27 does not affect Cx37>^−/− platelets confirming its selectivity.

Platelet aggregation performed in the presence or absence of ^37,43Gap27 (100 μg ml⁻¹) using washed platelets obtained from Cx37^+/+ (a) and Cx37^−/− (b) mice was recorded for 180 s following stimulation with CRP-XL (0.5 μg ml⁻¹). The level of aggregation obtained in the absence of ^37,43Gap27 was taken as 100%. Data represent mean±s.d. (n=3; Student’s t-test, *P<0.05).