Figure 6: A detailed comparison of active sites from our structure and 3U1N. | Nature Communications

Figure 6: A detailed comparison of active sites from our structure and 3U1N.

From: Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase

Figure 6

Close-up view of differences in the active sites. The residues in our structure are shown as blue sticks that bind the substrate directly. The corresponding residues in 3U1N are shown as purple sticks. The side chains of R366 and Q375 of 3U1N are oriented in different directions.

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