Table 1 Summary of logistic regression results for rs11098403 across cohorts.
From: Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder
Sample | Ethnicity | Case diagnosis | Total samples | Controls | Cases | MAF controls | MAF cases | Odds ratio | Additive P -value | Reference (see supplement) |
---|---|---|---|---|---|---|---|---|---|---|
Discovery | ||||||||||
Ashkenazi* | Caucasian | Schizophrenia | 2,544 | 1,640 | 904 | 0.38 | 0.47 | 1.41 | 6.55E−09 | |
Replication/extension | ||||||||||
MGS EA | Caucasian | Schizophrenia | 4,942 | 2,056 | 2,886 | 0.27 | 0.28 | 1.05 | 0.127 | 49 |
ZHH | Caucasian | Schizophrenia | 317 | 140 | 177 | 0.29 | 0.32 | 1.15 | 0.208 | 50 |
MGS AA* | African–American | Schizophrenia | 1,875 | 954 | 921 | 0.25 | 0.27 | 1.09 | 0.12 | 49 |
Japan* | Asian | Schizophrenia | 1,080 | 530 | 550 | 0.16 | 0.17 | 1.06 | 0.238 | 51 |
Munich | Caucasian | Schizophrenia | 842 | 412 | 430 | NA | NA | 1.1 | 0.287 | 52 |
Aberdeen | Caucasian | Schizophrenia | 892 | 441 | 451 | NA | NA | 1.21 | 0.03 | 52 |
GAIN | Caucasian | Bipolar | 1,710 | 689 | 1,021 | 0.25 | 0.28 | 1.13 | 0.058 | 53 |
German | Caucasian | Bipolar | 1,982 | 1,300 | 682 | 0.29 | 0.31 | 1.05 | 0.255 | 54 |
WTCCC | Caucasian | Bipolar | 4,806 | 2,938 | 1,868 | 0.25 | 0.27 | 1.1 | 0.019 | 55 |
Taiwan* | Asian | Bipolar | 2,000 | 1,000 | 1,000 | 0.15 | 0.16 | 1.06 | 0.25 | 56 |
Ashkenazi* | Caucasian | Bipolar | 2,745 | 2,531 | 214 | 0.38 | 0.43 | 1.24 | 0.0177 | |
All cohorts excluding discovery | 23,191 | 12,991 | 10,200 | 1.09 | 1.46E−07 | |||||
All cohorts | 25,735 | 14,631 | 11,104 | 1.13 | 9.49E−12 |