Figure 2: CS synthesis after the CSI is lower in T1KO than in WT mice.
From: Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury
(a) Following SCI, CS expression 2 weeks after the injury was considerably lower in T1KO mice than in WT or T2KO mice. Anti-CS-A and anti-CS-D antibodies recognize two distinct sugar chain units of CS. Scale bar, 1 mm. (b) CS accumulation following SCI was lower in T1KO than in WT mice. *P<0.05 (Student’s t-test; n=5). (c) CS(+) areas were smaller in T1KO (grey) mice than in WT (white) or T2KO (grey) mice. Repeated-measures ANOVA followed by the Bonferroni–Dunn test. *P<0.05 (n=6). Data are expressed as the mean±s.e.m. in b and c.
