Figure 4: Regional plots of two susceptibility loci for severe acne.
From: Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne
(a) 11p11.2 and (b) 1q24.2. For each plot, the –log10 P-values (left y-axis) of SNPs are presented according to their chromosomal positions (x-axis). The top genotyped SNP is labeled by rs ID, and the r2-values of the rest of the SNPs with the top genotyped SNP are indicated by different colours. The genetic recombination rates (estimated using the HapMap Han Chinese in Beijing (CHB) and Japanese in Tokyo (JPT) samples) are represented by light blue lines. Genes within the region are annotated and shown as arrows. P-values were generated using logistic regression.
