Figure 1: miR-33−/− mice become obese and develop hepatic steatosis.
From: MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice
(a) Development of BW of miR-33+/+ and miR-33−/− male mice fed NC. *P<0.05 versus NC-fed miR-33+/+ mice. Statistical comparisons were made by Student’s t-test. (b) Development of BW of miR-33+/+ and miR-33−/− mice fed or not fed HFD. *P<0.05 versus HFD-fed miR-33+/+ mice, #P<0.05 versus NC-fed miR-33+/+ mice. Statistical comparisons were made by one-way analysis of valiance test. (c) Representative image of miR-33+/+ and miR-33−/− mice fed with a HFD. Lower images show the livers of these mice. Scale bars, 1.0 cm. (d) Representative CT images of miR-33+/+ and miR-33−/− mice fed HFD. Values are the means±s.e.m.
