Table 1 Serum profile of miR-33+/+ and miR-33−/− on NC or HFD.

From: MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

 

miR-33 +/+ NC ( n =8)

miR-33 −/− NC ( n =8)

miR-33 +/+ HFD ( n =5)

miR-33 −/− HFD ( n =5)

AST (IU l−1)

67.63±5.43

56.50±11.89

53.80±2.89

134.40±18.48**

ALT (IU l−1)

39.38±6.02

41.00±11.95

31.40±3.92

167.40±29.15**

ALP (IU l−1)

186.88±15.29

238.13±14.57*

138.80±9.83

210.60±20.79*

T-CHO (mg dl−1)

85.75±3.83

110.25±6.16**

157.40±13.25

244.8±21.42**

TG (mg dl−1)

35.63±4.39

34.50±4.82

21.80±2.33

17.60±3.72

NEFA (μEq l−1)

766.8±30.89

867.1±53.68

778±61.21

979±55.40*

LDL-C (mg dl−1)

5.50±0.63

6.88±0.72

11.40±0.51

26.00±5.30*

HDL-C (mg dl−1)

52.38±2.08

66.13±2.72**

79.00±4.71

83.60±1.25

  1. Values are the means±s.e.m. Statistical comparisons were made by Student’s t-test (*P<0.05, **P<0.01).
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