Figure 3: MTHFD2 protein expression in human tumours. | Nature Communications

Figure 3: MTHFD2 protein expression in human tumours.

From: Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

Figure 3

(a) Top, fraction of samples with none, weak, moderate or strong immunohistochemistry staining for MTHFD2 in transformed cells, across 16 solid tumour types. Bottom, same analysis as above for stromal cells. For each tumour type, tumours from nine to 12 individuals were examined. (b) Representative images from each of the 16 tumour types summarized in (a), exemplifying negative (N), weak (W), moderate (M) or strong (S) staining intensities. Up arrow, stromal cells; down arrow, cancer cells. Scale bar represent 100 μm.

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