Figure 3: The cardiac jelly in the 34c mutant becomes thicker. | Nature Communications

Figure 3: The cardiac jelly in the 34c mutant becomes thicker.

From: Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish

Figure 3

(a,f), Histological sections of hearts from wild-type and mutant embryos at 48 hpf, staining with H&E. The endocardium of the mutant was extremely shrunken and the space between the myocardium and endocardium was much wider than that of the wild-type. The AVC (a, arrow) disappeared in the mutant (f). (b–j) Hyaluronic acid staining (green) and nucleus staining (blue) of the hearts of wild-type (b–e) and kctd10 mutant (g–j) embryos at 48 hpf. The arrow in b indicates the endocardial cushions at AVC, where more HA is localized. (e,j) enlarged views of the atrium wall (boxed in d,i). CJ, cardiac jelly; EC, endocardial cells nuclei; MC, myocardial cells nuclei. Scale bars=0.05 mm.

Back to article page