Figure 1: Paternal MHC expression on trophoblast.
From: MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling
(a) Expression of paternal H-2Dd on gd9.5 trophoblast from B6 females impregnated by either B6 (top), D8 (middle) or BALB/c (bottom) males. BALB/c mice endogenously express H-2Dd. (b) H-2Dd and cytokeratin staining on control spleen cells. Scale bar=25 μm. (c) Representative sections of the distribution of NKp46+ DBA−(brown) and NKp46+ DBA+ (pink) uNK in the region of trophoblast invasion in the central decidua at gd9.5. Dashed lines demarcate the approximate boundary between invasive ectoplacental cone trophoblast and maternal decidua basalis. Scale bar=250 μm. DBA, Dolichos biflorus agglutinin.
