Figure 7: Myometrial abnormalities.
From: MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling
(a,b) Representative sections of the pregnant uterus from B6 females stained with haematoxilin and eosin (H&E) illustrating the size of the decidua basalis (a) and MLAp (b). Dashed lines demarcate the smooth muscle layers that define the borders of the MLAp towards decidua and uterine wall. Scale bars=100 μm. (c,d) Stereological evaluation of decidual (c) and MLAp (d) volumes. Pooled data from 4 litters per cross, n=13–15 implantation sites. P-values from unpaired Student’s t-tests. Means±s.e.m. P-values from unpaired Student’s t-tests. (e) Representative sections of expression of VEGF-A and corresponding negative control in the decidua and MLAp of B6- and D8-mated B6 females. Scale bars=250 μm. H&E, haematoxylin and eosin. MLAp, mesometrial lymphoid aggregate of pregnancy. VEGF, vascular endothelial growth factor.
