Figure 5: PlexA4 mediates Sema3A-induced dendritic localization of GluA2. | Nature Communications

Figure 5: PlexA4 mediates Sema3A-induced dendritic localization of GluA2.

From: Plexin-A4-dependent retrograde semaphorin 3A signalling regulates the dendritic localization of GluA2-containing AMPA receptors

Figure 5

(a) Knockdown of PlexA4 attenuated Sema3A-enhanced immunostaining of GluA2 in dendrites. This attenuation was rescued by expressing a PlexA4-EGFPres. Magnified images of boxed areas in upper panels are shown in lower panels. Arrowheads indicate axon. Normalized mean immunostaining intensity of dendrite per neuron is shown in b (n=50 neurons from three independent cultures). Scale bars, 50 μm (upper panel); 10 μm (lower panel). *P<0.01 by ANOVA compared with vehicle control. Data are presented as mean±s.e.m.

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