Table 1 Integrated outlier genes with prognosis-associated expression.
From: MTSS1 is a metastasis driver in a subset of human melanomas
Probe ID | Gene name (aliases) | P value (Wilcoxon rank-sum test) | Function |
|---|---|---|---|
201592_at | EIF3H (eIF3-gamma, eIF3-p40) | 0.025 | Component of eIF-3 complex; plays a role in translation |
203987_at | FZD6 (Hfz6, FZ-6) | 0.025 | Negative regulator of canonical Wnt/β-Catenin; promotes the expression of the non-canonical Wnt signalling members |
203037_s_at | MTSS1 (MIM, KIAA0429) | 0.027 | Modulates actin-cytoskeletal machinery through interaction with several proteins |
201469_s_at | SHC1 (SHCA, p66) | 0.029 | Encodes three isoforms; two smaller isoforms function as adaptors for Ras activation downstream of Receptor Tyrosine Kinase activation |
201551_s_at | LAMP1 (CD107a, LGP120) | 0.035 | Member of the family of membrane glycoproteins that present carbohydrate ligands to selectins |
218273_s_at | PDP1 (PPM2C, PDH) | 0.041 | Positively regulates the activity of pyruvate dehydrogenase complex |
200652_at | SSR2 (TRAPB, SSR-beta) | 0.045 | Endoplasmic reticulum (ER) membrane receptor that is involved in protein translocation across the ER membrane |
