Figure 1: ARF6 depletion decreases syntenin exosome release. | Nature Communications

Figure 1: ARF6 depletion decreases syntenin exosome release.

From: Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2

Figure 1

MCF-7 cells were treated with 2 different ARF6 RNAi (siARF6#1 and siARF6#2) or non-targeting RNAi (siCNT). Total cell lysates (a) and the corresponding exosomes (c) were analysed by western blotting for different markers, as indicated. Histograms represent mean signal intensities±s.d. in cell lysates or exosomes, relative to signals in siCNT cells or exosomes, calculated for n independent experiments (b,d). SDC1CTF; syndecan-1 C-terminal fragment. *P<0.05, **P<0.01, ***P<0.001 (Student’s t-test).

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