Figure 2: Path of the ErmBL compared with TnaC and SecM nascent chains. | Nature Communications

Figure 2: Path of the ErmBL compared with TnaC and SecM nascent chains.

From: Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide

Figure 2

(a–c) Comparison of cryo-EM structures of ErmBL-SRC, TnaC-SRC8 and SecM-SRC10, with a transverse section of the 50S subunit (grey) displaying the path of the respective nascent chains through the ribosomal tunnel. (d–f) Paths of the (d) ErmBL (teal), (e) TnaC8 (purple) and (f) SecM10 (brown) nascent chains. Erythromycin (ERY)11 is coloured red in (d) ErmBL-SRC, whereas the superimposed position of ERY is coloured white in (e) TnaC-SRC and (f) SecM-SRC.

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