Figure 3: Increased nuclear PCAF and H3K9ac following SNA but not DCA.
From: PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system
(a) IHC co-staining with PCAF and H3K9ac of L4-L6 DRG following Sham/SNA or Sham/DCA. Insert shows high nuclear expression of PCAF and H3K9ac after SNA. Scale bar, 50 μm. (b) IHC intensity density analysis reveals an increase in nuclear PCAF following SNA/Sham but not DCA/Sham. (c) Intensity density analysis of IHC stained with H3K9ac reveals a significant fold increase following SNA but not DCA when compared with respective Sham. Student’s t-test, error bars, s.e., *P<0.05, ***P<0.001, N=3 per group, performed in triplicate.
