Figure 2: Spike activity is rhythmically correlated with respiration. | Nature Communications

Figure 2: Spike activity is rhythmically correlated with respiration.

From: Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration

Figure 2

Single- (n=3) and multi-unit (n=9) spike activity was recorded in the whisker barrel cortex of two awake mice. The cross-correlations of spike activity with breathing was significant for 3/3 single units and 8/9 multi-unit recordings. (a) Inter-spike interval histogram of single-unit spike activity recorded over 10 min in the whisker barrel cortex of an awake mouse. Inset shows overlays of waveforms of the first (left) and last (right) 10 action potentials. (b) Cross-correlation of single-unit spike activity with respiration (time of onset of the inspiratory cycle). The blue line represents the raw cross-correlation. The black line represents the median of the distribution of surrogate correlations. Top and bottom red lines represent the 5th and 95th percentile of the surrogate correlation distribution, respectively (see Methods or details). Raw correlations were considered significant if cross-correlation values exceeded the 5 or 95 percentile boundaries of the surrogate correlation distributions.

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