Table 1 Number of mice showing peritoneal invasion and liver/lung metastasis.
From: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect
HCT-116 empty vector-transfected cells | HCT-116 DERL3-transfected cells | P -value | |
---|---|---|---|
Orthotopic implantation | |||
Peritoneal invasion | |||
No | 0 | 11 | |
Yes | 12 | 1 | <0.005 |
Liver metastasis | |||
No | 2 | 10 | |
Yes | 10 | 2 | <0.01 |
Lung metastasis | |||
No | 2 | 10 | |
Yes | 10 | 2 | <0.01 |
Spleen injection | |||
Liver metastasis | |||
No | 4 | 8 | |
Yes | 8 | 4 | 0.00734 |
Lung metastasis | |||
No | 3 | 10 | |
Yes | 9 | 2 | <0.05 |