Figure 7: Inverse correlation between the number of ultraviolet and blue cones synapsing with H3 HCs in lor mutants. | Nature Communications

Figure 7: Inverse correlation between the number of ultraviolet and blue cones synapsing with H3 HCs in lor mutants.

From: Transmission from the dominant input shapes the stereotypic ratio of photoreceptor inputs onto horizontal cells

Figure 7

(a,b) An example of an H3 HC labelled in Tg(sws1:GFP; sws2:mCherry) crossed in the lor background. Connectivity map is shown in (a). Arrowhead indicates an unusual invagination into a ultraviolet cone by two dendritic tips from the same HC. Dendritic tips of larval H3 HCs normally do not show such branching or co-innervation of the same pedicle. Scale bar, 5 μm. The inset shows a high magnification view of the tip indicated by the arrowhead. (c) Quantification of the mean number of dendritic tips invaginating a single ultraviolet cone in wild-type (ctr) and lor. Open circles represent the average value for individual H3 HCs. Error bars are s.e.m. (d) The number of blue and ultraviolet cones synapsing onto a given H3 HC (each circle) at 5.5 d.p.f. are plotted here for wild-type animals (ctr) and lor mutants. All control H3 HCs had a single dendritic invagination into a cone pedicle. In lor, however, some H3 HCs project two or more dendritic tips into the cone pedicle (multiple tips). R2 and P-value from Pearson correlation coefficient.

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